Simian Parvovirus Infection: A Potential Zoonosis
نویسندگان
چکیده
منابع مشابه
Simian parvovirus infection: a potential zoonosis.
INTRODUCTION Simian parvovirus (SPV) causes severe anemia in immunocompromised macaques. The closely related erythrovirus, parvovirus B19, causes anemia in susceptible humans and can be grown in human bone marrow mononuclear cells in vitro. We hypothesized that SPV may infect humans and replicate in human bone marrow mononuclear cells. METHODS Serum samples from handlers of an SPV-seropositiv...
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Simian parvovirus is a recently discovered parvovirus that was first isolated from cynomolgus monkeys. It is similar to human B19 parvovirus in terms of virus genome, tropism for erythroid cells, and characteristic pathology in natural infections. Cynomolgus monkeys were infected with simian parvovirus to investigate their potential usefulness as an animal model of human B19 parvovirus. Six adu...
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The transcription map of simian parvovirus (SPV), an Erythrovirus similar to Parvovirus B19, was investigated. RNA was extracted from tissues of experimentally infected cynomolgus macaques and subjected to reverse transcription-PCR with SPV-specific primers. The PCR products were cloned and sequenced to identify splice junctions. A total of 14 distinct sequences were identified as putative part...
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Congenital parvovirus infection was diagnosed in two liveborn premature infants born at 24 and 35 weeks of gestational age. The illnesses were associated with placentomegaly, petechial rash, edema, hepatomegaly, anemia and thrombocytopenia, respiratory insufficiency, and death at 5 and 6 days of age. The syndromes exhibited by these cases shared common but nonspecific features with other life-t...
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BACKGROUNDS: Heavy metal toxicity has confirmed to be a critical threat to animals’ health. It has been proved that heavy metals can cause immunosuppression. Although, it is said that damage of immune function plays a contributing role in the increasing incidence of infectious diseases. The increasing use of rural habitats by jackals make them suitable to monitor the impact of anthropogenic on ...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2004
ISSN: 0022-1899,1537-6613
DOI: 10.1086/425420